Flow Filtration Skid
All our Pharmaceutical equipment is manufactured using high-precision techniques like computer numeric control (CNC) machining to build specialised machinery that strictly adheres to Good Manufacturing Practice (GMP) standards. This production process relies on durable, hygienic materials like medical-grade stainless steel, which are meticulously cut, shaped, and assembled to ensure absolute safety, corrosion resistance, and operational reliability in cleanroom environments. Each machine is systematically calibrated, tested, and documented to meet rigid regulatory requirements before it is integrated into pharmaceutical production lines to safely process medications.
Pharmaceutical equipment relies on highly specialised, non-reactive materials to prevent contamination and withstand harsh chemical cleaning.
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316L Stainless Steel: The industry standard for product-contact parts. The "L" stands for low carbon, which prevents corrosion during welding. It also contains molybdenum, making it highly resistant to pitting from chlorides and acids
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304 Stainless Steel: Used primarily for structural frames, external housings, and non-contact components where extreme chemical resistance is not required
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PTFE (Teflon) & PEEK: High-performance polymers used for seals, gaskets, and bearings. They offer excellent thermal stability, low friction, and zero chemical leaching
Flow Filtration Skid Renders
GMP (Good Manufacturing Practice) Design Requirements:
Under GMP guidelines, machinery must be engineered to prevent contamination and allow for effortless sanitisation.
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Surfaces in contact with product must have a low surface roughness.
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Equipment must be designed without sharp internal corners, dead legs, or exposed threads where product could get trapped and stagnate. Internal corners are machined with generous radii to allow complete drainage.
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All welds must be fully penetrated, ground smooth, and polished to be sanitary. Standard threaded fasteners are avoided in product zones; sanitary tri-clamp fittings are used instead.
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All internal fluid pathways and external surfaces must be sloped for self-draining. This ensures that cleaning solutions drain completely during Clean-in-Place (CIP) cycles, leaving no standing pools.
SciLog® TFF Systems are automated bioprocessing systems for tangential flow filtration applications such as diafiltration and concentration (ultrafiltration/microfiltration).
Utilising single-use assemblies and sensing technology, the system is compatible with any brand of TFF hollow fibre or cassette filters ensuring, flexibility to fit Parker's automation capabilities to customer process specifications.
The SciLog® TFF Systems incorporate SciPres® II pressure sensor technology to automatically monitor, adjust and document pressure, flow rates and transmembrane pressure to prevent extreme pressure over the membrane. This, in turn, safeguards the filter to maximise its lifetime and efficiency.
In conjunction with Parker's single-use manifolds, SciLog® TFF Systems can be configured to achieve flow rates of between 0.33 and 83 L/min with options of peristaltic and diaphragm feed pumps available.
Equipment designed and manufactured in collaboration with Parker Hannifin Manufacturing - Gas & Filtration Division For more information visit www.parker.com
